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home > Next N ExoTran Premium Skin Booster - Exosomes containing PDRN > Next N ExoTran Premium Skin Booster - Exosomes containing PDRN
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Next N ExoTran Premium Skin Booster - Exosomes containing PDRNColor Update You may notice that the newer batch has a slightly lighter tone compared to earlier production. We are sharing this proactively so you can feel confident in the consistency and integrity of the product! The formulation itself remains unchanged. The concentration of Sodium DNA PDRN, our core active, has not been reduced, diluted, or modified in any way. The deeper amber tone seen in earlier batches was a natural result of how high density
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Color Update

You may notice that the newer batch has a slightly lighter tone compared to earlier production. We are sharing this proactively so you can feel confident in the consistency and integrity of the product! The formulation itself remains unchanged. The concentration of Sodium DNA PDRN, our core active, has not been reduced, diluted, or modified in any way.

The deeper amber tone seen in earlier batches was a natural result of how high density Sodium DNA interacts within the formula, particularly alongside riboflavin vitamin B2, which carries its own inherent yellow hue. However, we received feedback that the brown tone left after treatment was not as pleasant. We have been working closely with the manufacturer for months, and they were finally able to maintain the same ingredients while achieving a lighter appearance.

What we did was optimize the balance of certain non pigment supporting components within regulatory formulation standards. In other words, we increased the proportion of clearer supporting ingredients, allowing the overall tone to appear lighter while maintaining the same, or higher, concentration of all active ingredients. We are very happy with how it turned out and hope you enjoy it! :) 

 


Frequently Asked Questions

🧬 Let’s Talk About Exosomes — Exotran by Trandmi

 

After years of research to find the best solution for skin rejuvenation, we partnered with Korea’s leading bio lab specializing in exosomes. This collaboration ensures the highest safety and ethical standards while delivering outstanding results. Experience the transformative power of our premium skin booster, developed through cutting-edge science!

 

Key Features:
  • Advanced Formula: Backed by 30 years of research from Seoul National University and featured in over 240 scientific papers. Registered internationally as “Human Umbilical Mesenchymal Stem Cell Conditioned Media Extract.”
  • Multi-Active Ingredients: Enhanced with PDRN (50,000ppm), NMN (20,000ppm), Plant Exosomes, Glutathione (100ppm), and Niacinamide (100,000ppm) for optimal skin benefits.
  • Fragrance-Free & Colorant-Free: Gentle on the skin, suitable for all skin types.
  • Superior Absorption: The USC1994 substances are 1/1700 the size of pores, allowing for deeper penetration and maximum absorption without needing devices.


The Power of the Next N ExoTran Booster
Benefits: Unique Formula: Combines over 89 ingredients to enhance cell & skin regeneration, collagen synthesis, inflammation suppression, moisture retention and antioxidant effects.
Results: Brightens skin tone, reduces pigmentation, suppresses melanin production, increases moisture, strengthens skin barrier, improves elasticity, reduces in appearance of pores, wrinkles and scars, and can aide in hair loss.


Key Ingredients:

  • NMN 20000ppm(Nicotinamide Mononucleotide): Boosts collagen, improves elasticity, reduces inflammation, and supports DNA repair. Powerful anti-aging effect called 'medicine of rejuvenation'.
  • PDRN 50000ppm: Extracted from salmon testes, is 95% identical to human DNA, effective in repairing and regenerating damaged skin.
  • Plant-derived extracellular vesicles (EVs): Centella Asiatica Extract; anti-aging, ant-inflammatory, anti-bacterial and antioxidant properties.
  • Glutathione 100ppm: Promotes collagen production, brightens skin, offers skin-restoring and antioxidant benefits.
  • Niacinamide 100000ppm: Brightening, hydrating , anti-acne, soothing, minimizes pore size.
  • Human umbilical cord blood cell culture medium
    USC 1994 'youngest cell' ingredient: anti aging, stimulation of growth factor secretion. 

Photo Credit: @bboxbeauty

 

Can it be RETAILED? 

Yes, can be used daily. Client can use other creams/ steps in their routine to help blend into the skin and to avoid the feeling of skin tightness.


What to Expect When Using:

  1. Remaining product? Any left over product must be REFRIGERATED and used within a week after opening. 
  2. Tackiness? Normal! This is a skin booster loaded with more ingredients. Can use a toner to blot off excess but recommended you leave it on for best results). If client is applying at home, applying other product in their skincare routine will alleviate tackiness.
  3. Amber color on the skin? Normal! Comes from large amount of PDRN. 
  4. Finishing products/moisturizers OK? Yes! Tradmi recommends PDRN Cream for Glass skin, though safe to use with your favorite. 
  5. # Treatments: Series of 3, advanced wrinkle reduction/ firming/ pore reduction/smoothing, and after 5 a greater brightening effect.
  6. Extra product in the Vial after treatment?  Make sure to apply generously during treatment, and give the client to take home! They can use small about daily and apply moisturizer and spf. 
  7. Post treatment: Client doesn’t wash skin until the next day.

As our reps and partners are aware, we have been exploring various exosome vendors over the years. Given the nature of umbilical cord blood cell culture, we were keen on collaborating with a reputable and prominent vendor to ensure safety and achieve the best results. As a result, extensive time was dedicated to researching, and we are pleased to announce that we have partnered with the largest bio lab in Korea specializing in Exosomes! They have conducted over 255 clinical studies and have successfully registered under INCI as "Human Umbilical Mesenchymal Stem Cell Conditioned Media Extract," not only in Korea but also internationally.

 


Also, keep in mind that aside from USC 1994, the product contains PDRN 50000ppm, NMN 20000ppm, Plant Exosomes, Glutathione 100ppm, and Niacinamide 100000ppm. This is THE BEST EXOSOME PRODUCT of all exosomes you can find in the market!

 


*We only support companies that do no harm and operate ethically!


Frequently Asked Questions

 

We want to make this absolutely clear — your skin cannot be irritated from the ExoTran product. We guarantee it. Exotran is formulated specifically for use during microneedling or microchanneling on freshly treated skin. Every ingredient is selected for safety on an “open channel” — meaning it can be applied directly after the skin has been perforated without causing chemical injury.

 

***If a client experiences unexpected burning, redness, or stinging, the cause is almost never the serum itself. More commonly, this can be related to factors such as: needle depth and number of passes, aggressive skin prep (acidic cleansers or alcohol), lingering numbing cream residue, recent sun exposure, certain medications, or even individual sensitivity to metal needles.

 

 

Because Exotran is biologically active, you may feel a temporary sensation as it penetrates — this is a sign the ingredients are engaging with the skin’s repair processes. However, prolonged or severe irritation is more likely due to treatment protocol variables rather than the serum composition. Adjusting prep, depth, or application method can usually eliminate this response while maintaining optimal result

 

 

 

To ensure you have complete professional confidence, we have broken down every single ingredient in the formula. This serum is made with purified water, peptides, over a dozen amino acids, sodium DNA (PDRN), NMN, centella asiatica, mugwort, plant extracts, vitamins, and gentle humectants — all medical-grade, clinically used ingredients specifically chosen to calm, repair, and rejuvenate skin immediately after microneedling. There are no exfoliating acids, no high-level alcohols, and no known irritants at concentrations that could damage the skin. Every active ingredient here is used to promote healing, calm inflammation, and enhance skin recovery.

 

In Korea, we’ve even used 3 vials per treatment safely — far more than typical — with zero irritation. The product itself is incapable of causing chemical burns or reactions. If redness or stinging persists, the cause lies elsewhere. 🙁

 

 

 

Here are 10 things we recommend you check when a client experiences irritation after microneedling — all based on the treatment process itself. There are certainly more possible factors, since skin type, current skin condition, seasonal changes, and even the client’s pre- and post-care at home can all play a role. 

 

Possible Causes of Post-Microneedling Reaction (Not Product-Related)

1. Treatment Depth – Needles going too deep for the client’s skin type can cause prolonged redness, swelling, or sensitivity.

2. Number of Passes – Excessive passes over the same area can create unnecessary trauma and increase inflammation. (We’ve seen cases where providers do too many passes simply because the skin doesn’t show an immediate reaction. This can lead to delayed irritation. We do not recommend more than 2–3 passes, and for very sensitive or thin skin, even a single pass is enough to gauge how the skin responds.)

3. Skin Prep Products – Harsh cleansers, degreasers, or pre-treatment solutions with high alcohol content can strip the skin barrier before microneedling.

4. Numbing Cream – Certain anesthetic creams contain preservatives or ingredients (like lidocaine, benzocaine, or prilocaine) that can cause skin sensitivity or allergic reactions.

5. Device Settings – Incorrect speed or power settings can damage skin tissue rather than gently stimulate it.

6. Needle Material Sensitivity – Some clients may have sensitivity to certain metals used in microneedling needles (especially nickel in lower-grade needles).

7. Post-Treatment Aftercare Products – Using incompatible skincare (acids, retinoids, fragranced creams) too soon after treatment can cause stinging and irritation.

8. Pre-existing Skin Conditions – Clients with rosacea, eczema, or highly sensitive skin may react more strongly to the treatment process.

9. Overheating or Over-drying During Healing – Excessive sun exposure, heat, or improper moisture levels post-treatment can lead to discomfort or delayed healing.

10. Improper Device Hygiene – Any residual disinfectant or contaminant on the needles or tip can cause an unexpected skin reaction.

 

The ingredients are the same, but they are just in different original forms!

 

 

Next N ExoTran Premium Skin Booster - Exosomes containing PDRN

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